Broken heart may be life threatening

Life-threatening risk factors in case of a broken heart

The fact that someone is a "broken heart" is not just a speech but also a medical reality. Takotsub's syndrome, also known as "broken heart syndrome", may even become life-threatening. Researchers now find out which patients are at increased risk in the short or long term.

Most patients recover without consequences

In the early 1990s, Takotsubo's syndrome (TTS) was first described by Japanese doctors Keigo Dote and Hikaru Sato. This disease occurs after intense mental stress, such as sadness or grief. Most women suffer after menopause. Most patients recover without disease. But ten percent will develop a dangerous complication. The study now identified patients who are at increased risk in the short or long term.

Most patients with Takotsubo syndrome ("broken heart syndrome") recover without the consequences of this disease. But some develop a dangerous complication. The study now identified patients who are at increased risk in the short or long term. (Picture: Di Studio /

The causes are not yet clear

The Takotsubo syndrome was a traditional, Japanese Octopus pike in the shape of a narrow neck with a narrow neck.

The special shape of the left ventricle at the end of the systole, which reminded her, was considered by the medical profession to be the result of a disturbance in the cardiac muscle system.

The causes of the disease are not yet clear and the treatment must therefore be based on symptoms.

The loss of a loved one will lure you

Because the illness often occurs due to strong emotional stress such as loss of beloved, emotional stress or grief, referred to as "broken heart syndrome" ("broken heart syndrome").

Also workplace bullying or extreme physical stress, such as surgery, a fall or a stroke, can cause a broken heart syndrome.

In addition, it could be shown that extremely positive events, such as marriage or winning the lottery, will earn Takotsub's syndrome.

Long-term risks

Meanwhile, it has become known in medicine that the illness may inter alia cause long-term heart damage and an increased risk of stroke.

Diseases can be fatal
Because the illness is a sudden onset, often a serious disorder of the heart pumping function, it is often first thought of a heart attack.

After the acute phase, most patients recover within a few weeks or months.

Approximately ten percent of patients, however, experience a cardiogenic shock associated with the acute phase, a life-threatening complication in which the heart suddenly pumps too little blood through the body.

Up to five percent of patients with cardiogenic shock die, says Zurich University Hospital (USZ).

Researchers at the USS have now discovered which Takotsubo patients are at increased risk for cardiogenic shock and have long-term consequences for the affected person.

Which patients develop a cardiogenic shock?

For their study, scientists could go back to the data collected in the InterTAK registry.

This first global Takotsubo registry was established in 2011 at the USZ Heart University Center to improve Takotsubo's syndrome research.

More than 40 cardiovascular centers from 20 countries are now in the registry; is led by prof. dr. copper. Dr. rer. nat. Christian Templin, Interventional Cardiologist and Head of Acute Cardiology at USZ.

"Thanks to this study, we now know which patients taking Takotsubo developed a cardiogenic shock in the acute phase of the disease and should therefore be monitored intensively," Templin said.

"These patients also have a long-term increased risk and should therefore be monitored continuously," says the expert.

These risk factors were little known and patients without abnormalities were not observed after Takotsubo's disease.

"Diagnosis, treatment, and prognosis of patients again took a significant step forward in this study." (Ad)

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