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The first child was born after the uterus was transplanted




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Uterine transplantation from deceased donors is feasible. A recent study, published by The Lancet, announcing the first birth of a child in Brazil on December 15, 2017,

The recipient was a female uterine infertility. One in 500 women with reproductive problems has problems with the uterine mucosa due to congenital anomalies or malformations, hysterectomies or unexpected infections. The only available options for a child are adoption or replacement pregnancy.

Before the Brazilian case, another ten uterine uterine transplants from dead donors were carried out in the United States, the Czech Republic and Turkey, but this is the first to give birth to a live birth.

However, doses between living and deceased persons have not yet been compared, nor surgical and immunosuppressive techniques that should be optimized in the future.

"The first transplantation of the uterus was a medical milestone, but the need for a living donor is an important limitation," says Dani Ejzenberg, a doctor at Das Clínicas Hospital at the University of São Paulo.

Find, step by step

The operation took place in September 2016. The recipient was a 32-year-old woman who was born without a uterus due to the Mayer-Rokitansky-Küster-Hauser syndrome, which affects one in every 4500 women. Four months before transplantation, she underwent an in vitro fertilization (IVF) cycle, resulting in eight fertilized eggs that were cryopreserved.

The donor was 45 years old and died of subarachnoid bleeding (a type of stroke that involves bleeding at the surface of the brain). The uterus was removed and transplanted to the patient in surgery, which lasted 10.5 hours. The operation involved the connection of the veins and arteries, ligaments and vaginal channels of the donated and receiving uterus.

After the procedure, the patient received immunosuppressive medications, as well as antimicrobial agents, anticoagulant treatment, and aspirin while in the hospital. Immunosuppression continued beyond the hospital until birth.

With information from SINC

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Uterine transplantation from deceased donors is feasible. A recent study, published by The Lancet, announcing the first birth of a child in Brazil on December 15, 2017,

The recipient was a female uterine infertility. One in 500 women with reproductive problems has problems with the uterine mucosa due to congenital anomalies or malformations, hysterectomies or unexpected infections. The only available options for a child are adoption or replacement pregnancy.

Before the Brazilian case, another ten uterine uterine transplants from dead donors were carried out in the United States, the Czech Republic and Turkey, but this is the first to give birth to a live birth.

However, doses between living and deceased persons have not yet been compared, nor surgical and immunosuppressive techniques that should be optimized in the future.

"The first transplantation of the uterus was a medical milestone, but the need for a living donor is an important limitation," says Dani Ejzenberg, a doctor at Das Clínicas Hospital at the University of São Paulo.

Find, step by step

The operation took place in September 2016. The recipient was a 32-year-old woman who was born without a uterus due to the Mayer-Rokitansky-Küster-Hauser syndrome, which affects one in every 4500 women. Four months before transplantation, she underwent an in vitro fertilization (IVF) cycle, resulting in eight fertilized eggs that were cryopreserved.

The donor was 45 years old and died of subarachnoid bleeding (a type of stroke that involves bleeding at the surface of the brain). The uterus was removed and transplanted to the patient in surgery, which lasted 10.5 hours. The operation involved the connection of the veins and arteries, ligaments and vaginal channels of the donated and receiving uterus.

After the procedure, the patient received immunosuppressive medications, as well as antimicrobial agents, anticoagulant treatment, and aspirin while in the hospital. Immunosuppression continued beyond the hospital until birth.

With information from SINC


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