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E-cigarettes pose less risk than combustible cigarettes, reveals Indian study



And first-ever Indian study found that Electronic Nicotine Delivery System (ENDS), also known as e-cigarettes, pose much less health risk than combustible cigarettes and could be an ideal tool to reduce or give up smoking.

Published in the Indian Journal of Clinical Practice (IJCP), the study, involving and "systematic review of 299 published scientific literatures", was conducted by Prof. R.N. Sharan and his team from North-Eastern Hill University, Shillong. It compared to the toxicities of nicotine, other chemicals and metal ions produced during cigarette smoking and use of e-cigarettes.

According to the team, "Regulatory measures to discourage cigarette smoking, the tobacco burden across the world has not shown significant decline over the years". In such a scenario, alternatives for tobacco harm reduction like ENDS or e-cigarettes, need to be evaluated.

Prof. Sharan told IANS: “This systematic review and meta-analysis is the first attempt by experts in India to audit the health and safety aspects of conventional cigarette smoking and ENDS in order to evaluate the suitability of ENDS as and less harmful alternative to conventional tuxedo. ”

The study authoritatively concluded that the newer generation ENDS was an efficient means of meeting the nicotine demand, and could help the cigarette smoking population quit the addiction and prevent tobacco harm reduction.

Among the key findings, the experts concluded that toxic chemicals such as carcinogens and other toxicants were found to be significantly higher in conventional cigarette smoke compared to vapor from an e-cigarette.

"For instance, metal ion Cadmium, which is a Class 1 carcinogen, and respiratory, reproductive and developmental toxicity, was found to be over 1,369 times higher in cigarette smoke than ENDS vapor. Similarly, Lead and Chromium, which are Class 2a probable carcinogens, were over 12 and 13 times more, respectively.

Cigarette smoke was also found to have significantly higher levels of Class 1 carcinogens such as formaldehyde (over 8 fold), benzene (22 fold) and NNK (over 92 fold), and Class 2a probable carcinogens, including acetaldehyde (over 91 fold) , Propanediol (over 53 fold) and Isoprene (over 17 fold), among others, in vapor of e-cigarette. ”

On the other hand, however, the study also found that Nickel, and Class 2b possible carcinogen, was four-fold more in e-cigarette vapor than in cigarette smoke.

The researchers also found that the risk of acute toxicity from direct ingestion of nicotine was highly unlikely to arise due to e-cigarette use. was in the range of 30-60 mg.

Speaking about the possible risks from physical makeup or design of ENDS devices, the study warned that, "Poor materials and build quality, lack of quality control and impression use of ENDS can give rise to potential accident hazard called" thermal runaway " lithium rechargeable batteries.

However, the experts added that "with technological advancement and optimization of safety features, these concerns can be adequately addressed."

Finally, the authors of the study found that “ENDS usage was higher among former smokers than non-smokers would be 4.13 fold, signifying that they could become a useful aid in smoking cessation.

"Also, use of ENDS was found to be 7.53 times higher in smokers than in non-smokers, which, contrary to perception, is less likely to be used by smokers to Reduce tobacco harm or quit smoking.

The team included Sambuddha Das and Dr. Yashmin Choudhury from Assam University, and Dr S. Thangminlal Vaiphei from Central University of Rajasthan.

Prof Sharan, who is a former president of the Indian Society for Radiation Biology, said: “By this study, we have called for rational policy making with the objective of maximizing benefits and minimizing potential risks by ENDS to smokers who choose to use them as a cessation tool, while preventing the ENDS from smokers, adolescents and children.

Published: April 30, 2019 10: 18 t



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