Israeli scientists human tissue transplant engineers use their own patient cells – Xinhua



Israeli scientists have developed a method for developing human tissues for transplanting the patient's small fat, said the University of Tel Aviv on Monday.

The method allows the patient to create any tissue in the body in a personalized manner without compromising the immune system.

So far, there have been witnesses of synthetic or animal substances that cause the immune response in a patient and therefore immunosuppressive drugs have been required.

In tissue engineering, synthetic or biological polymers are used as extracellular material to support cells and to enable the formation of functional tissue.

Until now, the extracellular material, which is now considered the best transplant, derives from pig tissue. In this process all pigs are removed and the remaining material grows with human cells.

However, the extracellular material of the pig also causes a severe immune response that can cause the implant to be rejected. The patient should also continue to take medication, sometimes throughout his life, which suppresses his immune system.

In order to find a solution, scientists removed the patient's minimal invasive adipose tissue process, separated the cells from the extracellular material, and formed a matched gel for the patient.

The fat cells were then "reprogrammed" into pluripotent stem cells, which can be transformed into all cell types.

Scientists have thus succeeded in tissue production to repair spinal cord injuries and treat damaged heart muscle, nerve tissue in patients with Parkinson's disease and tissue tissue for reconstructive surgery.

Since the tissue originates from the patient, they will not elicit an immune response. This technology has been successfully tested on animals and human immune cells.


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