Japanese scientists have introduced stem cells as part of efforts to treat Parkinson's disease in the brain, a study at the Kyoto University said today. They clarified that iPS stem cells, which have the ability to convert to any type of cell in the body, were introduced in men in the 1950s during the surgery they performed in October. The man is stable and will be supervised for two years, informs the French intelligence agency AFP.
IPS stem cells are adult stem cells that have been returned to embryonic stem cells by genetic modification.
In the left brain, 2.4 million stem cells of iPS-induced pluripotent stem cells were introduced. The procedure lasted for three hours. If the patient has no problem in the next six months, the same number of stem cells will be added to the right side of the brain. Stem cells derived from healthy donors have been developed into dopamine-producing brain precursors that die in patients with Parkinson's disease, AFP.
The University performed the aforementioned intervention when it was announced in July that this type of treatment would be tested in seven patients aged 50-69. They decided after successful experiments on monkeys that significantly improved their motor skills after the introduction of these iPS cells into the brain. In two years they did not develop tumors in the brain.
This is the first case of an attempt to treat Parkinson's disease by stem cell injection into the brain. Parkinson's disease is a chronic neurodegenerative disease whose cause is not known. Due to the disintegration of dopamine neurons in the brain, the disease is constantly evolving and can not be completely cured. The main motor symptoms are slow movement, stiffness of the muscles, tremors and disturbances of balance. Many non-motoric symptoms include emotional disorders, psychosis, sleep disorders, gastrointestinal disorders and various sensory problems.
In the world, according to the Parkinson's Disease, about 10 million people. About 7,000 patients with Parkinson's disease live in Slovenia.