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Mother with stomach leaked her caesarean scar is having a rare five-organ transplant



A mother whose insides began to burst through the caesarean section of the scar to undergo a rare five-organ transplant.

Michelle Oddy, 43, gave birth to her daughter, Kiera, via C-section in 2004, before her ordeal began.

Mrs Oddy, who has suffered from Crohn's disease since she was 14, woke up one morning to find her insides had pushed out of her scar, causing faeces to leak.

Doctors said it was caused by a fistula – an abnormal channel that passes from one organ to another, or outside the surface of the body. A fistula can be caused by Crohn's and other inflammatory bowel diseases.

Mrs Oddy's fistula was a channel from her bowel to her skin which then broke through the weak scar tissue of her C-section scar.

Mrs Oddy now has multiple organ failure, which doctors believe has been caused by various operations. She also has colostomy bag and relies on feeding tubes.

Surgeons have a chance to get their operation in the next two months to replace their liver, pancreas, small and large intestines and half of the stomach, with all the organs coming from one donor.

However, they have warned the hairdresser, from Ilkeston, Derbyshire, that is 35 per cent chance she will be during the 20-hour procedure.

Michelle Oddy, 43, of Ilkeston, Derbyshire, is a rare five-organ transplant after finding her insides bursting out of her caesarean section scar. Pictured at home with her colostomy bag and feeding machine

Michelle Oddy, 43, of Ilkeston, Derbyshire, is a rare five-organ transplant after finding her insides bursting out of her caesarean section scar. Pictured at home with her colostomy bag and feeding machine

Mrs Oddy woke up one morning to find her insides bursting out of her scar which had been caused by her Crohn's disease. Pictured, her stomach

Mrs Oddy woke up one morning to find her insides bursting out of her scar which had been caused by her Crohn's disease. Pictured, her stomach

With multiple organ failure due to many operations, and colostomy bag and feeding tubes constantly becoming infected, doctors are running out of options to keep Mrs Oddy going. Pictured when she dropped to four stone in 2015

With multiple organ failure due to many operations, and colostomy bag and feeding tubes constantly becoming infected, doctors are running out of options to keep Mrs Oddy going. Pictured when she dropped to four stone in 2015

Mrs Oddy said: 'The end of the day is only a matter of time before I could pass away. It just gets worse.

'My quality of life is so bad that I'm willing to gamble – half of my insides are being replaced.

'I want this gaping hole in my stomach to go, I can't do anything, it has completely taken over my life.'

Ms Oddy had endured seven operations to remove parts of her bowel due to complications with her Crohn's.

CAN INTERNAL ORGANS POP OUT OF A C-SECTION SCAR?

Mike Savvas, consultant at King Edward VII’s Hospital and King's College Hospital, London, said that while they are rare, 'they can happen'.

He told MailOnline in 2015: 'With any time of abdominal incision, this can happen – it's not unheard of.

'However, it is rare with horizontal incisions, as made during C-sections.

If there is a bit of gape then the bowel bulges out.

'It's not just a case of wound popping and everything spilling out.'

Another issue is that the new mothers have traditionally been in hospital for five days.

If an incident happens while a woman is on the ward, it is a lot quicker and easier – and less alarming – to deal with than at home, he explained.

In 2014, she woke up one morning and looked down to see her stomach in her years after the birth of her daughter. She did not say which month it happened in.

She said: 'The insides of my stomach were just falling out, there was blood all over me.' Mrs Oddy added that it was also leaking faeces.

Fistulas occur in one of three people with Crohn's at some point in their life, according to Crohn's and Colitis UK.

The abnormal passage may connect two parts of the bowel to each other, or the bow to the vagina, bladder, or skin, most commonly around the anus.

Mrs Oddy snake and gastrointestinal fistula, and passageway from the rest of her bowel to the outside of her stomach, which then broke through the skin where she had previously been opened for the C-section.

And gastrointestinal fistula causes fluids and acid to seep through the lining of the stomach or intestines which can cause infection to other organs and sepsis.

Food also struggles to move properly through the body.

It is not clear how Mrs Oddy's condition was treated, however, she still needs the hole dressed daily by nurses.

During this time, Mrs Oddy started to dramatically lose weight and gradually dropped to just four stone in 2015, which contributed to her organs struggling.

She said: 'It's hard to explain, but because I have had a lot of operations on my bowels, they've just worked out just clogs up in my body, and it has to leave somewhere.

'They told me my organs had packed up and I only had a few days of life left.'

Treated just in time, Mrs Oddy was given a TPN, or a liquid feed that was set up at her home after spending four weeks in hospital.

Mrs Oddy said: 'The insides of my stomach were just falling out, there was blood all over me'. Pictured, Mrs

Mrs Oddy said: 'The insides of my stomach were just falling out, there was blood all over me'. Pictured, Mrs

Mrs Oddy developed and fistula, which is an abnormal channel that passes from one organ to another, or outside the surface of the body. It's common in people with Crohn's

Mrs Oddy developed and fistula, which is an abnormal channel that passes from one organ to another, or outside the surface of the body. It's common in people with Crohn's

Mrs Oddy had 'one of the worst days of my life' last year when she fell ill and was rushed to hospital. She had gone into septic shock

Mrs Oddy had 'one of the worst days of my life' last year when she fell ill and was rushed to hospital. She had gone into septic shock

Six nights a week, and Mrs Oddy's home nurse visits the liquid feed, which gives her all the vital nutrients.

Mrs Oddy said: 'My weight started to get better but I have nurse coming to my house to feed me every day, it's just insane, I can't keep living like this.

'My organs have stopped working, I still have sticks in my stomach and a permanent colostomy bag.'

Mrs Oddy had 'one of the worst days of my life' last year when she fell ill and was rushed to hospital.

She said: 'My wife, Laura, walked in and found me unresponsive and staring into space.

'The next thing I remember was the room filling up with doctors. I had gone into septic shock due to the TPN and my veins giving in the pumped with the last four years.

'Once they have stabilized me, they told Laura to come in we could say our goodbyes because I wouldn't make it to the next day.

'Saying goodbye to my daughter, and Laura, was one of the hardest moments I have ever faced.

'Somehow, two hours later I made a full recovery and I decided to marry Laura six weeks later.'

Six nights a week, and Nursing visits Mrs Oddy's home to the liquid feed, which sends vital nutrients to her major arteries. Pictured at home with gastrostomy feeding machine and other medical equipment

Six nights a week, and Nursing visits Mrs Oddy's home to the liquid feed, which sends vital nutrients to her major arteries. Pictured at home with gastrostomy feeding machine and other medical equipment

After her weight plummeted in 2015, Mrs Oddy was given a TPN, or a liquid feed that was set up at her home after spending four weeks in a hospital

After her weight plummeted in 2015, Mrs Oddy was given a TPN, or a liquid feed that was set up at her home after spending four weeks in a hospital

Mrs Oddy shows a picture of the stomach in which he was blood and faeces

Mrs Oddy shows a picture of the stomach in which he was blood and faeces

The liver, pancreas, small intestine, large intestine and half of the stomach are all due to one donor

The liver, pancreas, small intestine, large intestine and half of the stomach are all due to one donor

WHAT IS A FISTULA?

A fistula is an abnormal connection between an organ and another structure. Fistulas develop when an organ becomes inflamed or injured.

They are very common complications of inflammatory bowel disease (IBD), occurring more frequently in Crohn's disease than ulcerative colitis.

About 35 per cent of people with Crohn's disease have at least one fistula.

The most common location for a fistula is around the anus. These are called perianal fistulas. Over half of fistulas form in this location. The second most common location is between two loops of intestine.

What are the symptoms?

Symptoms of Fistula Dependence on Where the Connection Has Formed. Fluid or waste may leak continually from the anus or vagina or seep through the wall of the abdomen.

If you have perianal fistula, you may have ongoing rectal pain or swelling.

A fistula between intestine and bladder can cause urinary tract infection that keeps returning.

Fistulas between two loops of intestine may not cause any symptoms.

What is the treatment?

Fistulas can be very complicated to treat. Surgery can be risky. Most health care providers will try to treat and perianal fistula with medication first.

However, many patients with perianal fistulas eventually do need surgery.

Now, consultants have said that their artificial feed is failing.

They have put her forward to have five of her organs replaced by giving her games a better quality of life.

She needs all of the organs to be from one donor to minimize the risk of rejection. The operation will also need a team of various surgeons to come together.

Mrs Oddy said: 'The idea that I have a 35 per cent chance of never waking up is terrifying.

'What I Always Remember is There's a 65 Percent Chance That I'll Wake Up Better, I'll Be My Daughter on a Holiday and We Can Be Swim Together.

'I want my quality of life back; I want to enjoy days out with my family just like everyone else.

'The little things have become difficult, I just want to enjoy a meal, or go out and have a worry about my stomach opening up and spilling out.

'Even for something as a picnic is hard – everyone is sitting around eating a lovely food and I can't touch it. I always have to be on guard. '

Cambridge University Hospitals NHS Foundation Trust consultant transplant surgeon, Andrew Butler, said: 'This procedure, which includes intestine graft, is rare and certainly complex.

'We have carried out about 100 such procedures and internationally there have been around 1,500 bowls containing transplants in adults since 1992.

'In the UK, Addenbrooke's Hospital is the only center that provides adult multivisceral transplants including a liver.'

Mrs Oddy said: 'Without my wife and daughter, who have been amazing throughout this whole process I would have already given up.

'I'm risking this for them, for better or for worse.'

What Is Crohn's Disease?

Crohn's disease is a long-term condition that causes inflammation of the digestive system.

Inflammation bridge commonly found in the last section of the small or large intestine but it can affect any part of the digestive system.

Common symptoms can include:

  • diarrhoea
  • abdominal pain
  • fatigue (extreme tiredness)
  • unintended weight loss
  • Blood and Mucus in Your Faeces (Stools) t

Remission occurs when people with disease go long periods of time without symptoms but these can be followed by flare ups of symptoms.

Why it happens

The exact cause of Crohn's disease is unknown. However, research suggests and combinations of factors may be responsible. These include:

genetics – genes you inherit from your parents may increase your risk of developing Crohn's disease

the immune system – the inflammation may be caused by a problem with the immune system that causes it to attack healthy bacteria in the gut

previous infection – a previous infection may trigger an abnormal response from the immune system

tuxedo – smokers with Crohn's disease usually have more severe symptoms than non-smokers

environmental factors – Crohn's disease is the most common in westernized countries such as the UK, and the least common in the world of Africa.

Source: NHS


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