Some more than others, but generally most people have hair in areas of the body like head, foot or arm, However, in others, such as palms of hands or foot soles, there is not even the smallest tinge of hair, regardless of gender, age or tendency to individual hair. Why is it?
This is a question many scientists have asked, and now a team of researchers from University of Pennsylvania Faculty of Medicine, in order to apply this knowledge to the treatment alopecia or restoring hair growth in Scars from burns and big wounds, In addition, its results, which were published today Cell reports, to explain why some animals, such as rabbits, have hair on areas of the body where other rodents, like a mouse, no.
Inhibits more "hairy" inscriptions
The gene encoding the signaling pathway inhibitor involved in the development of hair follicles is expressed on the hands and feet of the foot
These researchers focused on study WNT signaling path, which are known for their important role hair follicle development and hair growthIt is obvious that under normal conditions, this path works perfectly in body areas such as the legs or arms but does not work in other areas such as palms of hands,
The answer, as these scientists describe in their study, is protein inhibitor of said pathway, termed Dickkopf 2 (DDK2)., Check whether a gene that encodes this protein is found highly expressed in plantar skin of mice, in which, as in the soles of the human legs, no hair is produced. However, if it is inactive Hair begins to develop as well as in the rest of the body. This shows that the WNT is also located in these areas, but is paralyzed through action DDK2,
They finally found it in rabbits this gene is not expressed, so his skin, like polar bears, yes, she has my hair, This shows that this path was followed throughout this journey different ways, depending on the specific needs of each species animal
That's all a curious question that we have done so for a long time, but the goal of this team of scientists goes a long way.
It is known that hair follicles develop in human fetuses, but stop production after birth, Therefore, when a big blow or blow is burned, new skin lacks hairThey have suggested a solution to this problem make sure yes DDK2 of what concerns it in paralysis of the development of hair follicles; if so, in these specific cases it could be reactivated to favor new hair with hair.
But most of the worries about hair loss are people with alopecia. According to data from the Spanish Academy of Dermatology and Venerology (AEDV) 40% of men aged 18 to 39 suffers Androgenic alopecia, In addition, the percentage reaches 95% in men with age over 70 years,
Although it does not expect health problems, it is often accompanied by a major problem dissatisfied with the physical aspect, so many scientists are trying to find a solution. Previous studies have been found DKK2 like a potential candidate to the occurrence of this progressive hair loss, and therefore these researchers will also focus on the next steps of their work in the analysis. No doubt, if they manage to get a good harbor, many people will be happy with their findings.
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